Helmiban DS Vet - Albendazole

Helmiban DS Vet is a veterinary medicine of albendazole group and the therapeutic Group is Anthelmintic. This veterinary medicine is manufactured by Incepta Pharmaceuticals Limited.

Source - Incepta

Presentation

Helmiban DS Vet bolus: Each bolus contains Albendazole USP 1200 mg.

Description

Albendazole is a member of the Benzimidazole group of anthelmintic agents which is an ideal broad-spectrum anthelmintic. Albendazole inhibits polymerization of tubulin causes loss of cytoplasmic microtubules that leads to impaired uptake of glucose, depletes glycogen stores, degenerative change in the endoplasmic reticulum and mitochondria & decrease the production of ATP. It also inhibits the enzyme fumarate reductase which is a co-enzyme in many cellular oxidation-reduction reactions that result in no energy production and immobilization and death of parasites.

Indications

Albendazole is used as an anthelmintic against most nematodes and cestodes. It is effective against these gastro-intestinal parasites Bunostomum, Chabertia, Cooperia, Haemonchus, Ostertagia, Nematodirus, Strongyloides, Dictyocaulusviviparus, Monieziaexpansa, Liver flukes, and Paramphistomes. It is also effective against different types of worms, lung flukes, and lung nematodes.

Dosage & Administration

To keep animals free from helminths animals should be treated at 3 months interval.

Cattle & Buffalo: 7.5-10 mg/kg body weight or 14 bolus for 30-40 kg body weight, 12 bolus for 60-80 kg body weight & 1 boli for 120-160 kg body weight.

Goat & Sheep: 5-7.5 mg/kg body weight or 112 bolus for 13-20 kg body weight & 1 6 bolus for 27-40 kg body weight.

Dog & Cat: 15 mg/kg body weight or 18 bolus for 8-10 kg body weight & 14 bolus for 16-20 kg body weight.

Or as directed by the registered Veterinarian.

Side Effects

Albendazole is time tested and clinically proven well-tolerated drug. Established a wide safety margin than any other anthelmintic due to a greater selective affinity for parasitic b-tubulin than for animal tissues. However, in some cases, nausea and vomiting may occur.

Precautions

Before using Albendazole inform the registered Veterinarian that your animals are not allergic to it; or to other benzimidazole anthelmintic drugs (e.g. Mebendazole).

Use in Pregnancy & Lactation

Albendazole should not use the first 45 days of pregnancy of a cow. Do not administer to ewes or does during the first 30 days of pregnancy. Sufficient data on use during lactation is not available. Therefore breastfeeding should be discontinued during and for a minimum of 5 days after treatment.

Drug Interaction

Cimetidine, Praziquantel, and Dexamethasone have been reported to increase the plasma levels of Albendazole active metabolite.

OverDose

If poisoning or excessive overdosage is suspected, it is recommended for vomiting be induction or gastric lavage and such symptomatic supportive therapy to be administered.

Withdrawal Period

Milk: 2.5-3 days

Meat: Cattle: 14 days; Sheep & goat: 4 days

Storage

Do not store above 30 degrees centigrade. Keep away from light and out of the reach of children.

Commercial Pack

Helmiban DS Vet bolus: Each box contains 10 blisters of 2 boli.