Skip to main content

Duozol DS Vet bolus - Triclabendazole 1800 mg & Levamisole 1200 mg


Source - Incepta

Composition

Duozol DS vet bolus: Each bolus contains Triclabendazole INN 1800 mg and Levamisole Hydrochloride BP equivalent to Levamisole 1200 mg.

Description

The combination of Triclabendazole and Levamisoleis used for the treatment and control of fascioliasis, gastro-intestinal roundworms, and lungworms in cattle, sheep, and goats. Triclabendazole inhibits energy metabolism and Levamisole inhibits neuromuscular transmission of helminths. Levamisole acts on the neuromuscular junctions of nerves of nematodes as a ganglionic nicotinic acetylcholine agonist, causing muscular contraction of the worm and stimulates the parasympathetic and sympathetic ganglia of susceptible worms. It also interferes with carbohydrate metabolism in nematodes by blocking fumarate reduction and succinate oxidation. The overall effect is paralysis of the worm, allowing it to be expelled.

Indications

The combination is a broad-spectrum anthelmintic used against helminths in cattle, buffalo, sheep, goat, etc. The drug is used for the treatment of acute, sub-acute, and chronic fascioliasis due to the early immature and adult stages of Fasciola hepatica &Fasciolagigantica. It is also used against major parasites of ruminants such as Haemonchus and Ostertagia of the abomasum; Cooperia, Trichostrongylus, and Bunostomum of the small intestine; Oesophagustomum, Trichuris of the large intestine &Dictyocaulus spp. of the lungs. It is also used for the treatment of eye worms (Thelazia) of cattle.

Dosage & Administration

1 bolus for 150-180 kg b.w. or Triclabendazole 12 mg &Levamisole 8 mg per kg b.w. animal.
Triclabendazole and Levamisole bolus to be administered directly into the mouth of the animals, either by dissolving the tablet in water or given as drench or by mixing with molasses or by wrapping the tablet in a banana leaf.
Or as directed by the registered Veterinarian

Side Effects

The combination is well tolerated at the recommended dose. The safety index of Triclabendazole is about 16 times and the safety index of Levamisole is about 3 times the recommended dosage. But the safety index of a combination of Triclabendazole&Levamisole is 3 times the recommended dose.

Precautions

Adequate water should be fed during and after therapy.

Use in Pregnancy & Lactation

At the recommended dosage in pregnancy, no harmful effect has been reported. Moreover, no embryotoxic or teratogenic effects on fetuses have been reported.

Drug Interaction

This combination should not be used with Pyrantel, morantel, and diethylcarbamazine.

OverDose

Triclabendazole 16 times and Levamisole 3 times safe than the recommended dosages.

Withdrawal Period

Storage

Keep in a cool and dry place, away from light. Keep out of the reach of children.

Commercial Pack

Duozol DS vet bolus: Each box contains 10 blisters strip of Alu-PVC of 2 boli.

Labels:

Comments

Post a Comment

Popular posts from this blog

Relifen vet injection - Incepta

Source - Incepta Relifen vet injection is a veterinary medicine of generic class Ketoprofen 100 mg/ml and the therapeutic Group of this veterinary medicine is Animal Health. The manufacturer of Relifen vet injection is Incepta Pharmaceuticals Limited. Composition Relifen vet injection: Each ml contains Ketoprofen BP 100 mg. Description Ketoprofen injection is a potent, non-narcotic, and non-steroidal anti-inflammatory drug (NSAID) with analgesic, antipyretic and anti-inflammatory properties. Ketoprofen is US FDA approved NSAID, highly effective to alleviate pain, inflammation, and fever of dairy animals, a potent inhibitor of prostaglandin synthesis; it inhibits the biosynthesis of PGE2-a and PGF2-a without affecting the ratio of PGE2-a/PGF2-a. It is well tolerated up to 5 times than the recommended dose for 2-3 times longer than those used for treatment. Indications Ketoprofen injection is indicated in arthritis, arthritis, coxitis, dermatitis, post-operative wound & swelling, abs...
Post a Comment
Read more

Razinmax Vet - Piperazine Citrate 100% powder

  Source - Incepta Composition Razinmax Vet: Each gram powder contains Piperazine Citrate USP 1000 mg. Description Razinmax Vet is an anthelmintic with activity against nematodes (Roundworm). It closes neuromuscular transmission. As a result, the parasite suffers from flaccid paralysis and dies. Indications Razinmax Vet is used in infestations produced by nematode sensitive to Piperazineeg. Ascaris, Oxyuris, Strongyloides&Trichuris of poultry, cattle, buffaloes, horse, goat, sheep, and dog. Dosage & Administration 2 days250-500 mg/kg body weight or use 10 gm powder in 6-8 liter of drinking or 10 gm/3.5 kg feed for 100 chicken (4-6 weeks) or 50-60 pullet or 20-30 layers. 25-50 gm/100 kg body weight 4-8 gm/10 kg body weight 1-2.5 gm/10 kg body weight.Poultry Cattle, Buffalo & Horse Sheep & Goat Dog & Cat DurationDosageSpecies or as directed by the registered Veterinarian Side Effects Razinmax Vet is very safe. However, emesis and softening of the feces may be repo...
Post a Comment
Read more

Invemox 15% LA - ACI

Invemox 15% LA - ACI Invemox 15% LA Injection is a broad-spectrum antibiotic. It is indicated for the treatment of several bacterial diseases in cattle, buffalo, sheep, goat, dog, and cat. This veterinary medicine brought to the market by ACI Animal Health. Composition Each ml contains- Amoxicillin (trihydrate) 150 mg. Excipient q.s. 1 ml. Indications Invemox 15% LA Injection is a broad-spectrum antibiotic. It is indicated for the treatment of the several bacterial diseases in cattle, buffalo, sheep, goat, dog, and cat. Respiratory diseases: Pneumonia, bronchitis, calf diphtheria, sinusitis, Pharyngitis, laryngitis, etc. Reproductive diseases: Metritis, pyometra, postpartum infections retained placenta, cystitis, orchitis, etc. Urinary tract diseases: Acute renal failure,  pyelonephritis,  nephritis, etc. GI-Tract diseases: Gastritis, enteritis (Colibacillosis, Salmonellosis), calf scours. Local bacterial infections: Mastitis, abscess, wounds, bacterial eczem...
Post a Comment
Read more