Source - ACI |
- Composition
Each ml contains:
Trimethoprim |
40 mg |
Sulfathiazole |
40 mg |
Sulfadiazine |
60 mg |
Sulfamerazine |
100 mg |
Lidocaine hydrochloride |
1 mg |
- Mechanism of action
Trimethoprim - It binds to dihydrofolate reductase
enzyme & inhibits the reduction of dihydrofolic acid (DHF) to
tetrahydrofolic acid (THF) which is essential for bacterial synthesis. So
bacteria can’t survive.
Sulfathiazole - It inhibits microbial growth.
Sulfadiazine - It acts through inhibition of
dihydropteroate synthetase. Resistance arises through multiple mutations in
this gene.
Sulfamerazine - It inhibits folic acid synthesis by
acting as a competitive inhibitor of dihydropteroate synthetase, an enzyme found
in the folic acid synthesis pathway.
Lidocaine hydrochloride - It creates the anesthetic effect & preventing pain signals from propagating to the brain, but by stopping them before they begin.
- Indication
Bacterial infection of respiratory, alimentary and urogenital tract: bronchitis, pneumonia, diarrhea, metritis, arthritis, MMA, etc.
- Dosage & Administration
Inject the following dosage intramuscularly or
subcutaneously
Intramuscularly injection
Cattle : 7mL per 100kg body weight
Calf, sheep & goat: 4ml per 50kg bodyweight
Weaner: 1ml per 15kg bodyweight
Pack size - 50 ml bottle.
- Storage - Store in a cool and dry place, protected from light. Keep out of the reach of children.
Sulpha forte 4 আবার মার্কেটে আনা হোক
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